Research
For 60 years, the Department of Internal Medicine has held an annual Research Day to highlight and celebrate the scientific work of department faculty, fellows, residents, students, and science staff. It has grown from a half dozen posters to well over a hundred, settling in recent years to a manageable, competitive submission for 70 spots. Each year a team of faculty judges circulates among presenters on Research Day, listening to presentations and selecting best posters in basic and clinical/translational science as well as best poster by a new investigator. Winners receive a cash prize and time at Department of Internal Grand Rounds to present their work to a large and diverse audience of scientists and clinicians.
2026 Poster List
- Wenddy Sougey
Testosterone deficiency contributes to chronic stress-induced cardiac dysfunction, senescence, oxidative stress and inflammation in a genetic mouse model of dilated cardiomyopathy - Drew Bolisay
Impact of Adverse Childhood Experiences on Clinical, Physiological, and Self-Reported Outcomes in Multiple Sclerosis - Lauren Gray
Exploring the Association Between Adverse Childhood Experiences and Fatigue, Quality of Life, and Mood Among People with Multiple Sclerosis - Melia Patrick
The Feasibility, Challenges, and Facilitators of Implementing a Web-Based Behavioral Lifestyle Intervention to Improve Cancer-Related Fatigue and Quality of Life Among People with Cancer in Remission: A Mixed-Methods Study - Yue Jia
LSD1 Inhibition Activates STING and Potentiates STING Agonist Therapy by Upregulating ZDHHC7-Mediated STING Palmitoylation in Breast Cancer - Suryansh
MYELOID TLR4 SIGNALING DRIVES CYTOKINE-MEDIATED CD4+ T-CELL CYTOTOXICITY AND REDUCES PANCREATIC TUMOR BURDEN - Daisy Hernandez
CFTR Dysfunction Primes ILC2 for Enhanced Alarmin Signaling in the Airway - Kayla Henry - Oral Presentation
- Weijie Du
What powers ciliary beating in human airway epithelia - Maithreyi Prakash
Tuft-goblet cell axis in cystic fibrosis intestinal disease - Dilara Flor
Upper Extremity Osteomyelitis: A Multicenter, Retrospective Cohort Analysis within-Depth Assessment of Patient-Centered Outcomes at Iowa Health Care - Allison Rux
Myeloid Cell Tropism of JC Polyomavirus Drives Pathogenesis in Progressive Multifocal Leukoencephalopathy - Blake Bernauer
Cross-Lineage Suppression of JCPyV-Specific Immune Function in a Clinically Stratified PML Cohort - Allie Smith
Investigating the role of histone methylation modifier, LSD1, on BRCA1-mutated TNBC tumorigenesis and therapy resistance - Lei Tong
Central MANF Attenuates Endoplasmic Reticulum Stress-Induced Hemodynamic Responses and Sympathetic Outflow - Nicole Hristakos
Cardiac Intensive Care Unit Availability in Rural America: Insights from a Statewide Analysis in Iowa, USA - Elizabeth Wagstaff
Host-Viral Interactions Between Kidney and Glial Cells are Affected by Non-coding Control Region Rearrangements - Gokul Patil
Hemostatic potential of adjunctive rFVIIa or anti-TFPI in factor V deficiency - Gabby Bierlein-De La Rosa
Neuroendocrine Interactions Between GLP-1 and FGF21 in the Regulation of Alcohol-Related Behavior and Metabolism - Kyle Luo
Diagnostic Accuracy of Single Spirometry - Connor Kirk
Cyclin C Regulates Drp1‑Dependent Mitochondrial Fission in Response to Metabolic and Cardiac Stress - Prabuddha Sarkar
Modulation of HLA-E Expression and Stability by JC Polyomavirus Infection - Rohini Roy
Metabolic licensing in naive T cells - Lorena Tran
Epigenetic inflammatory memory in airway basal cells amplifies viral RNA responses in vivo - Nicolas R. Johnston
Enhanced glucagon receptor signaling supports pancreatic β-cell compensation in response to nutrient stress - Grace Fritz
Characterizing the role of MUC5AC in airway mucociliary transport - Kimberly Dukes
Barriers and Opportunities for Discharge Antibiotic Stewardship Processes Across Veterans Health Administration Facilities: A Qualitative Study - Hosung Bae
Mapping Inter-organ Metabolic Flux via Integrated Arteriovenous Metabolomics and Isotope Tracing - Ayushi Sood - Oral Presentation
- Austin Paden
RIPK2 Kinase Activity Promotes Early Myeloid Cell Recruitment and Host Defense during Listeria monocytogenes Infection - Silma Subah Raisa
Beyond the Heart: Artificial Intelligence-Enabled ECG for Detection and Clinical Utility of Hyperkalemia - Ian Holtz-Hazeltine
Regulation of JCPyV Infection by Transcriptional Repressor Capicua (CIC) - Shreyashree Sarkar - Oral Presentation
- Etinosa Osamudiamen
PMEL- mediated regulation of Natural killer cell antitumor activity - Gagan Flora
MCT4 Links Lactate Transport to Platelet Function and Thrombosis - Mikayla Stahl
Successful Repeat Administration of Helper-Dependent Adenovirus Following Immunosuppression in Pig Airways - Mark Yorek - Oral Presentation
- Mitchell Riley
A mucin-5B variant associated with idiopathic pulmonary fibrosis may prolong survival in the general population - Andrea Milenia Benavides
The immunological impact of e-cigarettes on monocytes - Saurabh Saini
Distinct roles of ROS and CD47 in radiation-induced Red Blood Cell injury and mortality - Jayashree Jena
Brown adipocyte GDF15 regulates metabolic adaptation to cold stress via GFRAL-independent and sex-dependent mechanisms. - Atsushi Miyamoto
Ubiquitin-specific protease 19 protects against cigarette smoke-induced lung injury and epithelial stress - Sadie Solomon
The Effects of Areca Nut and Arecoline Exposure on Metabolism in Diabetes: A Community-Engaged Translational Research Study - Jackson W. Kilburg
Defining β-cell surface protein modifications in response to proinflammatory cytokine signaling. - Grant Ozaki
Patient Characteristics and Outcomes with Impella RP Flex Use in Cardiogenic Shock Related to Right Ventricular Failure (RVF): A Single-Center Analysis - Aparna Pathmanathan
TRPV4-mediated AP-1/NFATC2 signaling axis drives squamous reprogramming of airway basal cells - Jasmyn Hoeger
Characterization of Post-Transcriptional Regulatory Elements Controlling MED13L Reveals Mutation-Agnostic Therapeutic Strategies for MED13L Syndrome - Pooja Yadav
Hydrogen peroxide regulates platelet activation and thrombosis through calcium-dependent mechanisms in aging - John McFadden
Evaluation of Glutathione Peroxidase 1 inhibition in colon cancer - Mallory Wilson-Quay
Characterizing the Clinical, Socioenvironmental, and Biological Features of Diabetic Foot Ulcers to Improve Point-of-Care Decision-Making - Amira Zaher
Dissecting the Intersection Between Cytosolic Antioxidants and ER Redox Maintenance in β-cell Failure - AM Racila
Frequency of Sexual Health History Documentation and Sexually Transmitted Infection (STI) Screening in the Iowa City VA Health Care System - Kyle Current
Sex and Ionizing Radiation Modulate Reactive Oxygen Species in Neonatal Rat Cardiac Myocytes - Jin-Young Yoon
Mitochondrial ROS-Driven Late INa Promotes Ca2+ Overload and Triggered Arrhythmias in SIRT5 Loss-of-Function Mouse Hearts - Satya Murthy Tadinada
Perinatal changes in energy metabolism of airway epithelia - Yadel Berhanu
Role of Cilia Length in Regulating Airway Mucus Properties - Anna Hepfer
Identification of Potential Tumor-Immune Modulators using Spatial Proteogenomic Profiling of Patient-Derived Tissues - Mike Shlossman
CFTR functions as a negative regulator of calcium flux in human CD4⁺ T cells - Hunter Youngbear
PMEL as a Driver of Tumor-Intrinsic Changes in Melanoma - Levi Rosenboom
JC Polyomavirus Cell Specific Response to Inflammatory Cytokines - Lalit K. Gautam
Akt Activity is a Critical Regulator of Airway Epithelial Cell Fate Decisions - Chris King
Implications for CFTR Expression during Early Pancreatic Development - Heather Davila
Rural-Urban Veteran Differences in Dementia Specialty Care Utilization - Kristen Walker
Restructuring of Hospital Medicine Services to Facilitate an Early Discharge Initiative for Hospital Medicine - Shivangi Inamdar
BLA-derived gastrin-releasing peptide promotes sensitized and generalized defensive behavior after intense aversive experience - Lauren Schultz
Development of a Novel Bispecific Antibody for Enhanced Blood-Brain-Barrier Transport in SHIV-Infected Rhesus Macaques - Hanna Paton
The strong acute Th1 response generated by Cd47-/- mice is not sufficient to mediate long-term protection against Leishmania major infection - Brett Wineinger
CellSpy: A fully automated immunofluorescent image analysis tool. - Karle Kramer - Oral Presentation
- Sahana Nagarajan
Using Patient Cells and Tissues to Investigate VEGF Signaling in Pulmonary Lymphangioleiomyomatosis - Stephanie Carr
A Therapeutic Strategy for Enhancing Target Gene Expression Through Blockade of microRNA Binding Sites - Mohana Sunkara and Alex Rouwenhorst
Hypoxic basal stem cell expansion improves differentiation of human nasal airway epithelial cells in vitro. - Matieis Mayes
LOSS OF ITGA6 ACTIVATES P38 MAPK SIGNALING TO DRIVE SQUAMOUS CONVERSION OF HUMAN AIRWAY BASAL CELLS - Ava Vaillant
Validation of Repressive Post-Transcriptional Regulatory Elements to Determine Therapeutic Potential for Sodium Channelopathies - Matthew W. Holt
In-Silico Analysis of High Grade Serous Ovarian Cancer to Identify Novel Immune Modulators - Omar Rababh
Elucidation of intercalated disc transcriptomes implicates an essential role for Adenomatous Polyposis Coli protein in RNA trafficking and cardiac viability - Nisha K Jha
From microbiome remodeling to a defined metabolite cocktail for pressure-overload cardioprotection - Himanshu Jangid
High-Throughput In Vitro CRISPR Guide Screening Using TIDE Analysis to Enable Efficient In Vivo Mouse Knockout Models - Rachel M. Reed
Regulation of Airway Surface Liquid by the PGE2 Response in Secretory Cells and Ionocytes - Kathy Nguyen
TREM-1 promotes allergic airway inflammation through cDC2-mediated TH2 priming during sensitization
2026 Award Winners
Best Clinical Research Poster
- Kristin Walker – 1st
Restructuring of Hospital Medicine Services to Facilitate an Early Discharge Initiative for Hospital Medicine - AM Racila – 2nd
Frequency of Sexual Health History Documentation and Sexually Transmitted Infection (STI) Screening in the Iowa City VA Health Care System
Best Basic Science Poster
- Andrea Milenia Benavides – 1st
Chronic e-cigarette use in healthy young adults is associated with hyper-inflammatory monocyte function - Stephanie Carr – 2nd
A Therapeutic Strategy for Enhancing Target Gene Expression Through Blockade of microRNA Binding Sites
Best Trainee Poster
- Jasmyn Hoeger – 1st
Characterization of Post-Transcriptional Regulatory Elements Controlling MED13L Reveals Mutation-Agnostic Therapeutic Strategies for MED13L Syndrome - Kathy Nguyen – 2nd
TREM-1 promotes allergic airway inflammation through cDC2-mediated TH2 priming during sensitization
Best Poster by a Resident or Fellow
- Kyle Luo – 1st
Diagnostic Accuracy of Single Spirometry - Nicole Hristakos – 2nd
Cardiac Intensive Care Unit Availability in Rural America: Insights from a Statewide Analysis in Iowa, USA
Directors’ Choice Award Recipients
- Toward Optimal Treatment of Diabetic Peripheral Neuropathy (DPN: Interim Results from a Dose Finding Randomized Trial)
Mark Yorek, PhD, Professor, Division of endocrinology and Metabolism - CFTR gene repair by AAV-mediated base editing in cystic fibrosis pig airway epithelia
Karle Kramer, BA, Post-Bacc Research Intern, Division of Pulmonary Medicine (Pediatrics) - Nox2-dependent neutrophil reprogramming promotes NETosis and venous thrombosis in colorectal cancer
Shreyashree Sarkar, MS, Graduate Research Assistant, Division of Hematology, Oncology, and Blood & Marrow Transplantation - Brown Adipose Tissue-Derived Growth Differentiation Factor 15 Improves Survival Following Myocardial Infarction Through GFRAL-Independent Mechanisms
Ayushi Sood, BS, Graduate Research Assistant, Division of Endocrinology and Metabolism - vCdk8 and Cdk19 exhibit a synthetic rescue that maintains basal cardiac homeostasis in cardiomyocytes
Kayla Henry, BS, Graduate Research Assistant, Division of Cardiovascular Medicine
Research Day 2026
September 29, 2026
Agenda:
| Time | Session |
|---|---|
| 11:00-11:50am | Lunch available – MERF Atrium |
| 12:00-1:00pm | Keynote Presentation (Prem Sahai - 1110 MERF) Understanding COPD Pathogenesis and Heterogeneity Using Genetics, Multiple Omics, and Network Approaches Edwin Kepner Silverman, MD, PhD |
| 1:15-2:30pm | Invited Presentations (Prem Sahai - 1110 MERF)
|
| 2:45pm-4:00pm | Poster Session and Reception (MERF Atrium) Poster presenters are asked to be at their poster from 2:45-4:00 PM for poster judging. |